We are looking for an excellent candidate for a PhD in Geospatial modelling the spread of antimicrobial resistance in the environment, funded by the NERC Envision doctoral training programme, supervised jointly by myself, Stuart Marsh (Nottingham Geospatial Institute), Malcolm Bennett (School of Veterinary Medicine and Science) and Andrew Singer (Centre for Ecology and Hydrology). Details of the project are below. Please apply by 6th January on http://www.envision-dtp.org/portal/apply.php.
Our vision is to develop mathematical models that can predict AMR spread in the environment. Such modelling will require numerous factors, including: prevalence of ARGs and the relative role of different AMR sources, pathways, drivers and receptors. These models would be used to inform policy on the priorities for controlling AMR in agriculture and the wider natural environment and on the most appropriate specific actions following an outbreak of an AMR pathogen. They will also help prioritise AMR surveillance. Most mathematical modelling for the environmental spread of AMR operates locally, e.g. in a slurry tank, field soil or a WWTP, or a smaller still, e.g. a biofilm. A challenge is to develop predictive models at much larger environmental scales.
This PhD project will begin to address this challenge, by following four novel modelling approaches: incorporation of the heterogeneity of AMR agents; using a combination of deterministic and stochastic models to account for both microscopic and population level scales; up-scaling the current approaches to an environmental scale by using methods developed for geospatial modelling of pollutants; and calibrating the models with geospatially explicit environmental AMR surveillance data from our projects and those of our collaborators.
Applicants should hold a minimum of a UK Honours Degree at 2:1 level or equivalent in any relevant scientific discipline with considerable quantitative component (mathematics, physics, computer science, engineering). They must be able to evidence excellent mathematical and computer programming skills, a willingness to work across multi-disciplinary boundaries, including physical geography and microbiology.
Full studentships are available to UK/EU candidates who’ve been ordinarily resident in the UK throughout the 3-year period immediately preceding the date of an award. EU candidates who’ve not been resident in the UK for the last 3-years are eligible for “tuition fees-only” awards (no maintenance grant).